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Describe the differences between the oxidation of ketones and aldehydes in the Baeyer-Villiger oxidation.

In the Baeyer-Villiger oxidation, ketones and aldehydes undergo different oxidation reactions.

Ketones and aldehydes are both carbonyl compounds that can undergo oxidation in the Baeyer-Villiger reaction. However, they react differently due to differences in their chemical structure.

Ketones have two alkyl groups attached to the carbonyl carbon, while aldehydes have one alkyl group and one hydrogen atom attached to the carbonyl carbon. In the Baeyer-Villiger oxidation, ketones are oxidized to esters, while aldehydes are oxidized to carboxylic acids.

The mechanism of the Baeyer-Villiger oxidation involves the formation of a peracid, which reacts with the carbonyl compound to form an intermediate called an ester enolate or an acyl oxaziridine. In the case of ketones, the ester enolate is formed, which then undergoes rearrangement to form the ester product. In the case of aldehydes, the acyl oxaziridine is formed, which then undergoes hydrolysis to form the carboxylic acid product.

Overall, the Baeyer-Villiger oxidation is a useful method for the synthesis of esters and carboxylic acids from ketones and aldehydes, respectively. The different products obtained from the oxidation of ketones and aldehydes highlight the importance of understanding the chemical structure and reactivity of different functional groups.

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