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AP Biology Notes

3.4.7 Calvin Cycle and Carbohydrate Production

AP Syllabus focus:

‘ATP and NADPH from light reactions power Calvin cycle reactions in the stroma, producing carbohydrates from carbon dioxide.’

The Calvin cycle is the main pathway that converts inorganic CO₂ into energy-rich organic molecules. It occurs in the chloroplast stroma and uses ATP and NADPH to build carbohydrates.

Location and purpose

  • Occurs in the stroma of chloroplasts (the fluid-filled interior surrounding thylakoids).

  • Uses chemical energy from ATP and reducing power from NADPH (made by light-dependent reactions) to convert carbon dioxide into carbohydrate.

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Practice Questions

FAQ

Rubisco is relatively slow and abundant enzyme molecules are needed.

Its activity can constrain the rate of CO₂ fixation when other resources are available.

Partitioning depends on metabolic demand and stromal conditions.

Regeneration is prioritised to maintain cycle continuity; export increases when carbon supply exceeds immediate regeneration needs.

$P_i$ availability can affect ATP synthesis and the exchange of triose phosphates.

Low $P_i$ can reduce the capacity to sustain high flux through carbohydrate-forming steps.

Radioactive tracer studies (e.g., $^{14}CO_2$) can label early products.

The earliest heavily labelled stable products are 3-carbon intermediates, consistent with 3-PGA formation after fixation.

Rubisco can also catalyse reactions that do not yield sugars under certain conditions.

This can divert carbon away from carbohydrate formation, especially when internal CO₂ levels are low.

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