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IB DP Biology Questions

3.5 Genetic Modification and Biotechnology

Question 1

Which of the following is the primary purpose of Polymerase Chain Reaction (PCR)?

A. Modification of proteins

B. Amplification of DNA

C. Creation of recombinant DNA

D. Separation of DNA fragments by size

Question 2

What is the role of plasmids in genetic engineering?

A. To act as enzymes that cut DNA

B. To act as vectors for transferring genes

C. To separate DNA fragments by size

D. To amplify DNA sequences

Question 3

Which technique is primarily used for separating DNA fragments by size?

A. PCR

B. Genetic engineering

C. Gel electrophoresis

D. DNA profiling

Question 4

What is the main application of DNA profiling?

A. Amplifying DNA

B. Creating GMOs

C. Forensic science and paternity testing

D. Producing insulin in bacteria

Question 5

Which process involves the creation of recombinant DNA for producing products like insulin?

A. Gel electrophoresis

B. PCR

C. Genetic engineering

D. DNA profiling

Question 6

a) Explain the process of creating recombinant DNA using plasmids as vectors, and discuss its significance in producing insulin in bacteria. [4]

b) Describe the principle and procedure of gel electrophoresis and explain how it is used in DNA profiling. [4]

Question 7

a) Discuss the concept and steps of Polymerase Chain Reaction (PCR) and explain its various applications in medical diagnostics and forensic science. [4]

b) Explain the concept of co-dominance using the ABO blood group system as an example and discuss the genetic control of the Rh factor. [4]

Question 8

a) Discuss the creation and applications of genetically modified organisms (GMOs) in agriculture, highlighting the benefits and concerns associated with their use. [4]

b) Explain the concept of polygenic inheritance and discuss how it contributes to continuous variation in traits such as skin colour and height. [4]

Question 9

a) Outline the steps involved in the process of genetic engineering to produce recombinant DNA. [3]

b) Discuss how Polymerase Chain Reaction (PCR) is used to amplify DNA and mention its significance in forensic science. [4]

c) Explain the concept of multiple alleles using the ABO blood group system as an illustration. [3]

Question 10

a) Describe the principle and procedure of gel electrophoresis and its application in DNA fingerprinting. [4]

b) Discuss Mendel's laws of segregation and independent assortment, illustrating with examples from pea plants. [4]

c) Explain how genetic modification in agriculture has raised both benefits and concerns. [2]

Question 11

In which field is PCR NOT typically used?

A. Medical diagnostics

B. Forensic science

C. Agriculture GMO creation

D. Paleobiology

Question 12

What is the primary purpose of using gel electrophoresis in DNA profiling?

A. Amplification of DNA

B. Transferring genes

C. Separation of DNA fragments by size

D. Creation of recombinant DNA

Question 13

Which of the following is NOT a step in Polymerase Chain Reaction (PCR)?

A. Denaturation

B. Annealing

C. Ligation

D. Extension

Question 14

What is the role of plasmids in the production of insulin in bacteria?

A. Amplifying the insulin gene

B. Separating insulin from other proteins

C. Acting as vectors for the insulin gene

D. Modifying the structure of insulin

Question 15

Which technique is essential for studying biodiversity and genetic genealogy?

A. Gel electrophoresis

B. Genetic engineering

C. DNA profiling

D. PCR

Question 16

a) Discuss the concept of co-dominance and how it is exemplified by the ABO blood group system. [3]

b) Explain the process and applications of Polymerase Chain Reaction (PCR) in medical diagnostics. [4]

c) Describe the role of plasmids as vectors in the creation of recombinant DNA. [3]

Question 17

a) Explain the concept of polygenic inheritance and how it results in continuous variation in traits like height. [3]

b) Discuss the procedure and principle of gel electrophoresis in separating DNA fragments. [4]

c) Describe how genetic engineering has been utilised for insulin production in bacteria. [3]

Question 18

a) Describe the creation of recombinant DNA using plasmids as vectors. [3]

b) Explain the principle of Polymerase Chain Reaction (PCR) and discuss its applications in paleobiology. [4]

c) Discuss the concept of co-dominance and illustrate it with the ABO blood group system. [3]

d) Explain how gel electrophoresis separates DNA fragments and its significance in DNA profiling. [4]

Question 19

a) Discuss Mendel's laws of segregation and independent assortment with examples from pea plants. [4]

b) Explain the concept of multiple alleles and how it is exemplified by the genetic control of the Rh factor. [3]

c) Describe the process and applications of genetic engineering in agriculture to create GMOs. [4]

d) Discuss how polygenic inheritance leads to continuous variation, providing examples like skin colour. [3]

Question 20

a) Explain the steps involved in Polymerase Chain Reaction (PCR) and its significance in forensic science. [4]

b) Describe the principle and procedure of gel electrophoresis and its use in paternity testing. [4]

c) Discuss the concept of genetic modification and provide examples of its application in insulin production. [3]

d) Explain the concept of polygenic inheritance and how it contributes to genetic variation in a population. [3]

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