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IB DP Biology Questions

7.5 Gene Expression

Question 1

Which of the following elements is NOT involved in the regulation of gene expression at the transcriptional level?

A. Promoter sequences

B. Enhancers

C. Initiation factors

D. Silencers

Question 2

In the context of gene expression regulation, what is the primary function of RNA polymerase?

A. Synthesis of mRNA

B. Degradation of mRNA

C. Modification of mRNA

D. Transport of mRNA

Question 3

Which of the following is a post-transcriptional modification in eukaryotes?

A. Methylation of cytosine bases

B. Addition of a poly-A tail

C. Binding of transcription factors

D. Interaction with enhancers

Question 4

In prokaryotes, the regulation of the lac operon is an example of:

A. Positive inducible system

B. Negative inducible system

C. Positive repressible system

D. Negative repressible system

Question 5

Which of the following is NOT a method of gene expression regulation at the post-translational level?

A. Protein folding

B. RNA splicing

C. Protein modification

D. Protein degradation

Question 6

a) Discuss the role of promoters in gene expression and how they interact with RNA polymerase and transcription factors in eukaryotes. [4]

b) Explain the regulation of gene expression at the post-transcriptional level, focusing on RNA processing and RNA stability. [3]

Question 7

a) Describe the lac operon as an example of gene expression regulation in prokaryotes and explain its function. [4]

b) Discuss the role of transcription factors in regulating gene expression in eukaryotes, providing examples. [3]

Question 8

a) Explain how gene expression is regulated at the translational level, focusing on the role of initiation factors and codon usage. [3]

b) Discuss the significance of post-translational modifications in regulating gene expression and provide examples of such modifications. [4]

Question 9

a) Elaborate on the role of enhancers and silencers in the regulation of gene expression at the transcriptional level. [3]

b) Discuss how RNA stability contributes to the regulation of gene expression at the post-transcriptional level. [3]

c) Provide a detailed example of a post-translational modification and explain how it regulates gene expression. [4]

Question 10

a) Describe the structure of tRNA and explain its role in translation. [4]

b) Discuss the initiation stage of translation, highlighting the roles of various translation factors. [3]

c) Explain how the lac operon functions as a model of gene regulation in prokaryotes. [3]

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